Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms
Bile acids have been shown to inhibit human (h) carbonic anhydrases (CA, EC 4.2.1.1) along the gastrointestinal tract, including hCA II. The elucidation of the hormonal inhibition mechanism of the bile acid cholate to hCA II was provided in 2014 by X-ray crystallography. Herein, we extend the inhibi...
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Main Authors: | , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2018-01-01T00:00:00Z.
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A1234.567 |
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