Nucleotide analogues as inhibitors of SARS‐CoV Polymerase

• Auteurs principaux: Jingyue Ju (Auteur), Xiaoxu Li (Auteur), Shiv Kumar (Auteur), Steffen Jockusch (Auteur), Minchen Chien (Auteur), Chuanjuan Tao (Auteur), Irina Morozova (Auteur), Sergey Kalachikov (Auteur), Robert N. Kirchdoerfer (Auteur), James J. Russo (Auteur)
• Format: Livre
• Publié: Wiley, 2020-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract SARS‐CoV‐2, a member of the coronavirus family, has caused a global public health emergency. Based on our analysis of hepatitis C virus and coronavirus replication, and the molecular structures and activities of viral inhibitors, we previously reasoned that the FDA‐approved hepatitis C drug...