Fexinidazole: a potential new drug candidate for Chagas disease.

• Hauptverfasser: Maria Terezinha Bahia (Verfasst von), Isabel Mayer de Andrade (Verfasst von), Tassiane Assíria Fontes Martins (Verfasst von), Álvaro Fernando da Silva do Nascimento (Verfasst von), Lívia de Figueiredo Diniz (Verfasst von), Ivo Santana Caldas (Verfasst von), André Talvani (Verfasst von), Bernadette Bourdin Trunz (Verfasst von), Els Torreele (Verfasst von), Isabela Ribeiro (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

BACKGROUND: New safe and effective treatments for Chagas disease (CD) are urgently needed. Current chemotherapy options for CD have significant limitations, including failure to uniformly achieve parasitological cure or prevent the chronic phase of CD, and safety and tolerability concerns. Fexinidaz...