BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles

• Main Authors: Walter W Chen (Author), Leonora Balaj (Author), Linda M Liau (Author), Michael L Samuels (Author), Steve K Kotsopoulos (Author), Casey A Maguire (Author), Lori LoGuidice (Author), Horacio Soto (Author), Matthew Garrett (Author), Lin Dan Zhu (Author), Sarada Sivaraman (Author), Clark Chen (Author), Eric T Wong (Author), Bob S Carter (Author), Fred H Hochberg (Author), Xandra O Breakefield (Author), Johan Skog (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Development of biofluid-based molecular diagnostic tests for cancer is an important step towards tumor characterization and real-time monitoring in a minimally invasive fashion. Extracellular vesicles (EVs) are released from tumor cells into body fluids and can provide a powerful platform for tumor...