HIF1α deficiency reduces inflammation in a mouse model of proximal colon cancer
Hypoxia-inducible factor 1α (HIF1α) is a transcription factor that regulates the adaptation of cells to hypoxic microenvironments, for example inside solid tumours. Stabilisation of HIF1α can also occur in normoxic conditions in inflamed tissue or as a result of inactivating mutations in negative re...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2015-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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