Simple and Accurate HPTLC-Densitometric Method for Quantification of Delafloxacin (A Novel Fluoroquinolone Antibiotic) in Plasma Samples: Application to Pharmacokinetic Study in Rats

• Main Authors: Prawez Alam (Author), Muzaffar Iqbal (Author), Essam Ezzeldin (Author), Nasr Y. Khalil (Author), Ahmed I. Foudah (Author), Mohammed H. Alqarni (Author), Faiyaz Shakeel (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Delafloxacin (DLX) is a recently-approved fluoroquinolone antibiotic, which is recommended for the treatment of “acute bacterial skin and skin structure infections”. A thorough literature survey revealed only a single published method for the estimation of DLX using UPLC-MS/MS te...