AEG-1 is involved in hypoxia-induced autophagy and decreases chemosensitivity in T-cell lymphoma

• Main Authors: Jiaqin Yan (Author), Junhui Zhang (Author), Xudong Zhang (Author), Xin Li (Author), Ling Li (Author), Zhaoming Li (Author), Renyin Chen (Author), Lei Zhang (Author), Jingjing Wu (Author), Xinhua Wang (Author), Zhenchang Sun (Author), Xiaorui Fu (Author), Yu Chang (Author), Feifei Nan (Author), Hui Yu (Author), Xiaolong Wu (Author), Xiaoyan Feng (Author), Wencai Li (Author), Mingzhi Zhang (Author)
• Format: Book
• Published: BMC, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study was to examine the link between astrocyte elevated gene-1 (AEG-1) and hypoxia induced-chemoresistance in T-cell non-Hodgkin's lymphoma (T-NHL), as well as the underlying molecular mechanisms. Methods Expression of AEG-1, LC3-II, and Beclin-1 were initially examine...