Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl4/2-AAF

• Main Authors: Ying Xu (Author), Wen Xu (Author), Wei Liu (Author), Gaofeng Chen (Author), Shili Jiang (Author), Jiamei Chen (Author), Xun Jian (Author), Hua Zhang (Author), Ping Liu (Author), Yongping Mu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Our previous studies indicated that Yiguanjian decoction (YGJ) has an anti-hepatic-fibrosis effect and could regulate macrophage status. Objective To elucidate the mechanism of YGJ in regulating macrophages. Materials and methods Liver cirrhosis was induced by CCl4 for 12 weeks combined with...