Dihydrotestosterone regulates oxidative stress and immunosuppressive cytokines in a female BALB/c mouse model of Graves' disease

• Main Authors: Fengyi Zhao (Author), Liping Wu (Author), Yue Wang (Author), Lianye Liu (Author), Fei Yang (Author), Yushi Sun (Author), Xiang Jiao (Author), Lingyu Bao (Author), Pu Chen (Author), Qiangrong Liang (Author), Bingyin Shi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Graves' disease (GD) is an autoimmune disease that affects more women than men. In our previous study, a potent bioactive androgen, 5α-dihydrotestosterone (DHT) showed a protective effect against GD in female BALB/c mice. Evidence indicates that abnormal oxidative stress and immunos...