Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer

• Main Authors: Leda Severi (Author), Lorena Losi (Author), Sergio Fonda (Author), Laura Taddia (Author), Gaia Gozzi (Author), Gaetano Marverti (Author), Fulvio Magni (Author), Clizia Chinello (Author), Martina Stella (Author), Jalid Sheouli (Author), Elena I. Braicu (Author), Filippo Genovese (Author), Angela Lauriola (Author), Chiara Marraccini (Author), Alessandra Gualandi (Author), Domenico D'Arca (Author), Stefania Ferrari (Author), Maria P. Costi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Proteomics and bioinformatics are a useful combined technology for the characterization of protein expression level and modulation associated with the response to a drug and with its mechanism of action. The folate pathway represents an important target in the anticancer drugs therapy. In the presen...