Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila

• Auteurs principaux: Samuel H. Friedman (Auteur), Neil Dani (Auteur), Emma Rushton (Auteur), Kendal Broadie (Auteur)
• Format: Livre
• Publié: The Company of Biologists, 2013-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

SUMMARY Fragile X syndrome (FXS), the most common inherited determinant of intellectual disability and autism spectrum disorders, is caused by loss of the fragile X mental retardation 1 (FMR1) gene product (FMRP), an mRNA-binding translational repressor. A number of conserved FMRP targets have been...