Automated radiofluorination of HER2 single domain antibody: the road towards the clinical translation of [18F]FB-HER2 sdAb

• Autori principali: Herlinde Dierick (Autore), Laurent Navarro (Autore), Sonja Van den Block (Autore), Jelena Saliën (Autore), Tony Lahoutte (Autore), Vicky Caveliers (Autore), Jessica Bridoux (Autore)
• Natura: Libro
• Pubblicazione: SpringerOpen, 2024-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background With the next generation of Human Epidermal Growth Factor Receptor 2 (HER2) -targeting therapies, such as antibody-drug conjugates, showing benefit in "HER2 low" and even "HER2 ultralow" patients, the need for novel methods to quantify HER2 expression accurate...