Automated radiofluorination of HER2 single domain antibody: the road towards the clinical translation of [18F]FB-HER2 sdAb

• Main Authors: Herlinde Dierick (Author), Laurent Navarro (Author), Sonja Van den Block (Author), Jelena Saliën (Author), Tony Lahoutte (Author), Vicky Caveliers (Author), Jessica Bridoux (Author)
• Format: Book
• Published: SpringerOpen, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background With the next generation of Human Epidermal Growth Factor Receptor 2 (HER2) -targeting therapies, such as antibody-drug conjugates, showing benefit in "HER2 low" and even "HER2 ultralow" patients, the need for novel methods to quantify HER2 expression accurate...