Amphotericin B release rate is the link between drug status in the liposomal bilayer and toxicity

• Үндсэн зохиолчид: Yuri Svirkin (Зохиогч), Jaeweon Lee (Зохиогч), Richard Marx (Зохиогч), Seongkyu Yoon (Зохиогч), Nelson Landrau (Зохиогч), Md Abul Kaisar (Зохиогч), Bin Qin (Зохиогч), Jin H. Park (Зохиогч), Khondoker Alam (Зохиогч), Darby Kozak (Зохиогч), Yan Wang (Зохиогч), Xiaoming Xu (Зохиогч), Jiwen Zheng (Зохиогч), Benjamin Rivnay (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2022-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Amphotericin B (AmB) is an amphiphilic drug commonly formulated in liposomes and administered intravenously to treat systemic fungal infections. Recent studies on the liposomal drug product have shed light on the AmB aggregation status in the bilayer, which heat treatment (curing) modifies. Although...