Inverse Agonistic Activity of Antihistamines and Suppression of Histamine H1 Receptor Gene Expression
Histamine H1 receptor (H1R) expression influences the severity of allergy symptoms. We examined the effect of inverse agonists on H1R gene expression. Two inverse agonists (carebastine and mepyramine), but not the neutral antagonist oxatomide, decreased inositol phosphate accumulation. The inverse a...
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| Auteurs principaux: | , , , |
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| Format: | Livre |
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Elsevier,
2012-01-01T00:00:00Z.
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