An Esterase-Responsive SLC7A11 shRNA Delivery System Induced Ferroptosis and Suppressed Hepatocellular Carcinoma Progression

• Main Authors: Hui Zhang (Author), Jianguo Wang (Author), Xiaonan Xiang (Author), Chang Xie (Author), Xinfeng Lu (Author), Haijun Guo (Author), Yiyang Sun (Author), Zhixiong Shi (Author), Hongliang Song (Author), Nasha Qiu (Author), Xiao Xu (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis has garnered attention as a potential approach to fight against cancer, which is characterized by the iron-driven buildup of lipid peroxidation. However, the robust defense mechanisms against intracellular ferroptosis pose significant challenges to its effective induction. In this paper,...