Inhibition of Autophagy Contributes to Melatonin-Mediated Neuroprotection Against Transient Focal Cerebral Ischemia in Rats

• Main Authors: Yongqiu Zheng (Author), Jincai Hou (Author), Jianxun Liu (Author), Mingjiang Yao (Author), Lei Li (Author), Bo Zhang (Author), Hua Zhu (Author), Zhong Wang (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Melatonin, a natural product of the pineal gland, has been shown to protect against ischemic stroke, but the molecular mechanisms underlying its protective function are not fully understood. In the present study, we tested whether melatonin could protect against ischemia- reperfusion (I/R) injury to...