A Stromal Cell-Derived Factor 1α Analogue Improves Endothelial Cell Function in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome

• Main Authors: Changrun Guo (Author), Andrew Goodwin (Author), Joy N Jones Buie (Author), James Cook (Author), Perry Halushka (Author), Kelley Argraves (Author), Basilia Zingarelli (Author), Xian Zhang (Author), Liping Wang (Author), Hongkuan Fan (Author)
• Format: Book
• Published: BMC, 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Endothelial cell (EC) dysfunction is a critical mediator of the acute respiratory distress syndrome (ARDS). Recent studies have demonstrated that stromal cell-derived factor 1α (SDF-1α) promotes EC barrier integrity. Our previous studies used a SDF-1α analogue CTCE-0214 (CTCE) in experiment...