Controllable release of pirfenidone by polyvinyl alcohol film embedded soft contact lenses in vitro and in vivo

• Main Authors: Caiqing Wu (Author), Ping Wai Or (Author), Jones Iok Tong Chong (Author), Isuru K. K. Pathirage Don (Author), Ching Hymn Christopher Lee (Author), Kaili Wu (Author), Minbin Yu (Author), David C. C. Lam (Author), Yangfan Yang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To increase the amount of pirfenidone (PFD) loaded in polyvinyl alcohol (PVA) film embedded soft contact lens (SCL), and evaluate its function of sustaining delivery of drug in vitro and in vivo. Drug loading efficiency within PVA film and SCLs, drug release from SCLs in vitro, and the effects of pa...