Neural Differentiation Is Inhibited through HIF1α/β-Catenin Signaling in Embryoid Bodies

• Main Authors: Josef Večeřa (Author), Jana Kudová (Author), Jan Kučera (Author), Lukáš Kubala (Author), Jiří Pacherník (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extensive research in the field of stem cells and developmental biology has revealed evidence of the role of hypoxia as an important factor regulating self-renewal and differentiation. However, comprehensive information about the exact hypoxia-mediated regulatory mechanism of stem cell fate during e...