An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfection.

• Hoofdauteurs: Jonathan L M Fontes (Auteur), Ricardo Khouri (Auteur), Luis Gustavo C Reinaldo (Auteur), Erina M A Hassegawa (Auteur), Antônio José Meneses Filho (Auteur), Caroline V B de Melo (Auteur), Pablo Ivan P Ramos (Auteur), Rafael de Deus Moura (Auteur), Carla Pagliari (Auteur), Marta Santos (Auteur), Raimundo José C Araújo (Auteur), Johan Van Weyenbergh (Auteur), Luiz A R de Freitas (Auteur), Carlos Henrique N Costa (Auteur), Washington L C Dos-Santos (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2024-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The spleen plays a pivotal role in the pathogenesis of visceral leishmaniasis. In severe forms of the disease, the spleen undergoes changes that can compromise its function in surveilling blood-circulating pathogens. In this study, we present an integrated analysis of the structural and gene express...