QSAR Regression Models for Predicting HMG-CoA Reductase Inhibition

• Váldodahkkit: Robert Ancuceanu (Dahkki), Patriciu Constantin Popovici (Dahkki), Doina Drăgănescu (Dahkki), Ștefan Busnatu (Dahkki), Beatrice Elena Lascu (Dahkki), Mihaela Dinu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2024-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background/Objectives: HMG-CoA reductase is an enzyme that regulates the initial stage of cholesterol synthesis, and its inhibitors are widely used in the treatment of cardiovascular diseases. Methods: We have created a set of quantitative structure-activity relationship (QSAR) models for human HMG-...