S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis

• Main Authors: Salvatore Rizza (Author), Claudia Cirotti (Author), Costanza Montagna (Author), Simone Cardaci (Author), Claudia Consales (Author), Mauro Cozzolino (Author), Maria Teresa Carrì (Author), Francesco Cecconi (Author), Giuseppe Filomeni (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative and nitrosative stresses have been reported as detrimental phenomena concurring to the onset of several neurodegenerative diseases. Here we reported that the ectopic modulation of the denitrosylating enzyme S-nitrosoglutathione reductase (GSNOR) differently impinges on the phenotype of two...