The Possible Molecular Mechanism of SARS-CoV-2 Main Protease: New Structural Insights from Computational Methods

• Principais autores: Alvea Tasneem (Autor), Gyan Prakash Rai (Autor), Saima Reyaz (Autor), Hridoy R. Bairagya (Autor)
• Formato: Livro
• Publicado em: Ital Publication, 2021-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Main protease (Mpro) is one of the key enzymes in the life cycle of SARS-CoV-2 that plays a pivotal role in mediating viral replication, transcription, and makes it an attractive drug target for this virus.  The catalytic site of this enzyme comprises of a dyad His41 and Cys145 and lacks the third c...