Lack of Atorvastatin Effect on Monocyte Gene Expression and Inflammatory Markers in HIV-1- infected ART-suppressed Individuals at Risk of non-AIDS Comorbidities

• Main Authors: Anjana Yadav (Author), Andrew Kossenkov (Author), Louise Showe (Author), Sarah Ratcliffe (Author), Grace Choi (Author), Luis Montaner (Author), Pablo Tebas (Author), Pamela Shaw (Author), Ronald Collman (Author)
• Format: Book
• Published: Case Western Reserve University, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Many people living with HIV have persistent monocyte activation despite viral suppression by antiretroviral therapy (ART), which contributes to non-AIDS complications including neurocognitive and other disorders. Statins have immunomodulatory properties that might be beneficial by reduci...