Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model.

• প্রধান লেখক: Frédéric-Antoine Dauchy (লেখক), Mélanie Bonhivers (লেখক), Nicolas Landrein (লেখক), Denis Dacheux (লেখক), Pierrette Courtois (লেখক), Florian Lauruol (লেখক), Sylvie Daulouède (লেখক), Philippe Vincendeau (লেখক), Derrick R Robinson (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2016-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with HAT. Sterol 14alpha-demethylase (CYP51) is a poten...