Oral administration of MnCl2 attenuated hyperlipidemia-related cardiac remodeling in ApoE−/− mice

• Main Authors: Han-Xiao Zhang (Author), Cheng-Shun Zhang (Author), Rui-Zhen Huang (Author), Xin Cao (Author), Xiao-Qin Dai (Author), Chuan-Yi Zuo (Author), Peng Lv (Author), Li-Juan Zhu (Author), Shu-Guang Yu (Author)
• Format: Book
• Published: Elsevier, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Manganese chloride (MnCl2) has been shown to inhibit the Yes-associated protein (YAP) in high-fat diet-fed ApoE−/− mice. Although YAP has been implicated in atherogenesis, there are limited data on the effects of MnCl2 on cardiac remodeling. In this study, we discovered, by electrocardiography, that...