Inhibition of Scavenger Receptor Class B Type 1 (SR-B1) Expression and Activity as a Potential Novel Target to Disrupt Cholesterol Availability in Castration-Resistant Prostate Cancer

• Autori principali: Mitali Pandey (Autore), Grace Cuddihy (Autore), Jacob A. Gordon (Autore), Michael E. Cox (Autore), Kishor M. Wasan (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

There have been several studies that have linked elevated scavenger receptor class b type 1 (SR-B1) expression and activity to the development and progression of castration-resistant prostate cancer (CRPC). SR-B1 facilitates the influx of cholesterol to the cell from lipoproteins in systemic circula...