Development and optimization of sitagliptin and dapagliflozin loaded oral self-nanoemulsifying formulation against type 2 diabetes mellitus

• Autori principali: Mohsin Kazi (Autore), Abdulmohsen Alqahtani (Autore), Ajaz Ahmad (Autore), Omar M. Noman (Autore), Mohammed S. Aldughaim (Autore), Ali S. Alqahtani (Autore), Fars K. Alanazi (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Control of hyperglycemia and prevention of glucose reabsorption (glucotoxicity) are important objectives in the management of type 2 diabetes. This study deals with an oral combined dosage form design for two anti-diabetic drugs, sitagliptin and dapagliflozin using self-nanoemulsifying drug delivery...