M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis.

• Main Authors: Debanjan Mukhopadhyay (Author), Shibabrata Mukherjee (Author), Susmita Roy (Author), Jane E Dalton (Author), Sunanda Kundu (Author), Avijit Sarkar (Author), Nilay K Das (Author), Paul M Kaye (Author), Mitali Chatterjee (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The high level of functional diversity and plasticity in monocytes/macrophages has been defined within in vitro systems as M1 (classically activated), M2 (alternatively activated) and deactivated macrophages, of which the latter two subtypes are associated with suppression of cell mediated immunity,...