Enzyme-instructed and mitochondria-targeting peptide self-assembly to efficiently induce immunogenic cell death

• Main Authors: Debin Zheng (Author), Jingfei Liu (Author), Limin Xie (Author), Yuhan Wang (Author), Yinghao Ding (Author), Rong Peng (Author), Min Cui (Author), Ling Wang (Author), Yongjie Zhang (Author), Chunqiu Zhang (Author), Zhimou Yang (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immunogenic cell death (ICD) plays a major role in cancer immunotherapy by stimulating specific T cell responses and restoring the antitumor immune system. However, effective type II ICD inducers without biotoxicity are still very limited. Herein, a tentative drug- or photosensitizer-free strategy w...