The effects of a hirudin/liposome complex on a diabetic nephropathy rat model

• Main Authors: Hongwu Wang (Author), Huantian Cui (Author), Lan Lin (Author), Yue Ji (Author), Qing Ni (Author), Junchen Li (Author), Jianli Pang (Author), Gongyan Bing (Author), Yuhong Bian (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hirudin, an extract from Hirudo spp., is an anticoagulant used to treat a variety of renal diseases, including diabetic nephropathy (DN). Currently, hirudin has to be used at high dosages to treat DN because it poorly targets the kidneys, although at high dosages it can have seve...