The effect of hydrophilic and hydrophobic polymers on release profiles of diclofenac sodium from matrix tablets

• Main Authors: Md Imamul Islam (Author), Md Kamal Hossain (Author), Taksim Ahmed (Author), Prabhat Bhusal (Author), Md Sohel Rana (Author), Tanveer A Khan (Author)
• Format: Book
• Published: Archives of Global Professionals, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The current study aimed to develop a matrix type sustained release Diclofenac tablet, using hydrophilic hydroxypropyl methylcellulose (HPMC) and hydrophobic polymer cetyl alcohol (CA). Materials and Methods: Two different polymers, that is, Methocel K15MCR® and CA were used in various pro...