Upregulation of ATP-Sensitive Potassium Channels as the Potential Mechanism of Cardioprotection and Vasorelaxation Under the Action of Pyridoxal-5-Phosphate in Old Rats

• Main Authors: Ruslan B. Strutynskyi PhD, DSc (Author), Nataliіa A. Strutynska PhD (Author), Oksana O. Piven PhD, DSc (Author), Lidiia A. Mys PhD (Author), Yulia V. Goshovska PhD (Author), Raisa A. Fedichkina PhD (Author), Iryna Y. Okhai (postgraduate) (Author), Vladyslav R. Strutynskyi PhD student (Author), Victor E. Dosenko MD, PhD, DSc (Author), Pawel Dobrzyn PhD, DSc (Author), Vadim F. Sagach MD, PhD, DSc (Author)
• Format: Book
• Published: SAGE Publishing, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The aging process is accompanied by the weakening of the protective systems of the organism, in particular by the decrease in the expression of ATP-sensitive potassium (K ATP ) channels and in the synthesis of H 2 S. The aim of our work was to investigate the role of K ATP channels in th...