Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis

• Glavni autori: Yong Mou (Autor), Guo‐Rao Wu (Autor), Qi Wang (Autor), Ting Pan (Autor), Lei Zhang (Autor), Yongjian Xu (Autor), Weining Xiong (Autor), Qing Zhou (Autor), Yi Wang (Autor)
• Format: Knjiga
• Izdano: Wiley, 2022-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by the infiltration of macrophages in the fibrotic region. Currently, no therapeutic strategies effectively control disease progression, and the 5‐year mortality of patients after diagnosis is unacc...