Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis

• Главные авторы: Yong Mou (Автор), Guo‐Rao Wu (Автор), Qi Wang (Автор), Ting Pan (Автор), Lei Zhang (Автор), Yongjian Xu (Автор), Weining Xiong (Автор), Qing Zhou (Автор), Yi Wang (Автор)
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• Опубликовано: Wiley, 2022-05-01T00:00:00Z.
• Предметы: article
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Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by the infiltration of macrophages in the fibrotic region. Currently, no therapeutic strategies effectively control disease progression, and the 5‐year mortality of patients after diagnosis is unacc...