Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase

• मुख्य लेखकों: Ahmed H. E. Hassan (लेखक), Yeon Il Oh (लेखक), Chae Hyeon Lee (लेखक), Yeon Ju Kim (लेखक), Soo Bin Cho (लेखक), Md. Maqusood Alam (लेखक), Sang-Eun Park (लेखक), Kyung-Sook Chung (लेखक), Kyung-Tae Lee (लेखक), Yong Sup Lee (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Phenethyl-based edelfosine-analogs with saturated, monounsaturated, or polyunsaturated alkoxy substituents on phenyl ring were designed as novel antitumor lipids modulating p38 MAPK. Evaluation of the synthesised compounds against nine panels of diverse cancer cells presented saturated and monounsat...