Diagnostic accuracy of an in-house Scrub Typhus enzyme linked immunoassay for the detection of IgM and IgG antibodies in Laos.

• Main Authors: Philip N D Elders (Author), Sandhya Dhawan (Author), Ampai Tanganuchitcharnchai (Author), Koukeo Phommasone (Author), Vilada Chansamouth (Author), Nicholas P J Day (Author), Jose A Garcia-Rivera (Author), Jeffrey C Hertz (Author), Mayfong Mayxay (Author), Manivanh Vongsouvath (Author), Audrey Dubot-Pérès (Author), Matthew T Robinson (Author), Paul N Newton (Author), Stuart D Blacksell (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scrub typhus is a major cause of morbidity and mortality in Southeast Asia. Diagnosis of scrub typhus is difficult due to a lack of accessible validated diagnostic tools. Despite its objectivity, the diagnostic accuracy of ELISA tests is influenced by methodological and patient factors. This study a...