Quantitative pulmonary pharmacokinetics of tetrandrine for SARS-CoV-2 repurposing: a physiologically based pharmacokinetic modeling approach
Tetrandrine (TET) has been traditionally used in China as a medication to treat silicosis and has recently demonstrated anti-SARS-CoV-2 potential in vitro. By recognizing the disparity between in vitro findings and in vivo performance, we aimed to estimate the free lung concentration of TET using a...
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Main Authors: | Furun Wang (Author), Liuhan Dong (Author), Juanwen Hu (Author), Shijie Yang (Author), Lingchao Wang (Author), Zhiwei Zhang (Author), Wenpeng Zhang (Author), Xiaomei Zhuang (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2024-09-01T00:00:00Z.
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