Molecular profiling of individual FDA-approved clinical drugs identifies modulators of nonsense-mediated mRNA decay
Nonsense-mediated mRNA decay (NMD) degrades transcripts with premature stop codons. Given the prevalence of nonsense single nucleotide polymorphisms (SNPs) in the general population, it is urgent to catalog the effects of clinically approved drugs on NMD activity: any interference could alter the ex...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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