Role of IRF4 in the Protection of Metformin-Mediated Sepsis Myocarditis

• Główni autorzy: Minghua Li (Autor), Hongmei Yu (Autor), Yonglin Wang (Autor), Ling Qin (Autor), Wei Sun (Autor)
• Format: Książka
• Wydane: SAGE Publishing, 2019-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Aims: Metformin has been shown to play a protective role in diabetes. However, we found that metformin could mediate myocardial protection. Given that protein kinase C eplison (PKCε) and interferon regulatory factor 4 (IRF4) are critical for cardioprotection signaling. And measurement of fluorescenc...