Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids

• Главные авторы: Peter Bitsch (Автор), Eva S. Baum (Автор), Irati Beltrán Hernández (Автор), Sebastian Bitsch (Автор), Jakob Harwood (Автор), Sabrina Oliveira (Автор), Harald Kolmar (Автор)
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• Опубликовано: MDPI AG, 2023-09-01T00:00:00Z.
• Предметы: article
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Here we report the generation of nanobody dextran polymer conjugates (dextraknobs) that are loaded with small molecules, i.e., fluorophores or photosensitizers, for potential applications in cancer diagnostics and therapy. To this end, the molecules are conjugated to the dextran polymer which is cou...