1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1

• Main Authors: Takaishi Masayuki (Author), Fujita Fumitaka (Author), Uchida Kunitoshi (Author), Yamamoto Satoshi (Author), (Shimizu) (Author), (Uotsu) (Author), Shimizu Mayumi (Author), Tominaga Makoto (Author)
• Format: Bog
• Udgivet: SAGE Publishing, 2012-11-01T00:00:00Z.
• Fag: article
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<p>Abstract</p> <p>Background</p> <p>Essential oils are often used in alternative medicine as analgesic and anti-inflammatory remedies. However, the specific compounds that confer the effects of essential oils and the molecular mechanisms are largely unknown. TRPM8 is a...