Downregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis

• Glavni autori: Weijie Liang (Autor), Ruibin Wei (Autor), Xingxing Zhu (Autor), Jinliang Li (Autor), Aiwen Lin (Autor), Jun Chen (Autor), Wen Wu (Autor), Qiang Jie (Autor)
• Format: Knjiga
• Izdano: BMC, 2024-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background Macrophage-derived extracellular vesicle (macrophage-EV) is highly studied for its regulatory role in atherosclerosis (AS). Our current study tried to elucidate the possible role of macrophage-EV loaded with small interfering RNA against high-mobility group box 1 (siHMGB1) affect...