Azoxystrobin Induces Apoptosis of Human Esophageal Squamous Cell Carcinoma KYSE-150 Cells through Triggering of the Mitochondrial Pathway

• Main Authors: Xiao-ke Shi (Author), Xiao-bo Bian (Author), Tao Huang (Author), Bo Wen (Author), Ling Zhao (Author), Huai-xue Mu (Author), Sarwat Fatima (Author), Bao-min Fan (Author), Zhao-xiang Bian (Author), Lin-fang Huang (Author), Cheng-yuan Lin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies indicate that mitochondrial pathways of apoptosis are potential chemotherapeutic target for the treatment of esophageal cancer. Azoxystrobin (AZOX), a methoxyacrylate derived from the naturally occurring strobilurins, is a known fungicide acting as a ubiquinol oxidation (Qo) inhibitor...