Pharmacogenetic Study of the Impact of <i>ABCB1</i> Single Nucleotide Polymorphisms on the Response to Cyclosporine in Psoriasis Patients

• প্রধান লেখক: Alexandr Chernov (লেখক), Daria Kilina (লেখক), Tatiana Smirnova (লেখক), Elvira Galimova (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Psoriasis is a chronic, T cell-mediated skin disease affecting 2-3% of the Caucasian population. Cyclosporine A is a calcineurin inhibitor that acts selectively on T cells. The cyclosporine A treatment response has been suggested to be modulated by single-nucleotide polymorphisms (SNPs) in the <i...