Model Based Identification of Linezolid Exposure-toxicity Thresholds in Hospitalized Patients

• Main Authors: Jie Fang (Author), Xiao-Shan Zhang (Author), Chun-Hong Zhang (Author), Zi-Ye Zhou (Author), Lu Han (Author), Ye-Xuan Wang (Author), Xiao-Shuang He (Author), Xiao-Lan Bian (Author), Guan-Yang Lin (Author), Zheng Jiao (Author), Ying Dai (Author), Xu-Ben Yu (Author), Jing-Ye Pan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Evidence supports linezolid therapeutic drug monitoring as the exposure-response relationship has been identified for toxicity among patients receiving linezolid, but the data to establish the upper limit are limited and the published toxicity thresholds range widely. The purpose of this study was t...