Sarcoma and the 100,000 Genomes Project: our experience and changes to practice

• Main Authors: Sophie C Prendergast (Author), Anna‐Christina Strobl (Author), William Cross (Author), Nischalan Pillay (Author), Sandra J Strauss (Author), Hongtao Ye (Author), Daniel Lindsay (Author), Roberto Tirabosco (Author), Jane Chalker (Author), Shazia S Mahamdallie (Author), Alona Sosinsky (Author), RNOH Pathology Laboratory and Biobank Team (Author), Genomics England Research Consortium (Author), Adrienne M Flanagan (Author), Fernanda Amary (Author)
• Formato: Livro
• Publicado em: Wiley, 2020-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract The largest whole genome sequencing (WGS) endeavour involving cancer and rare diseases was initiated in the UK in 2015 and ran for 5 years. Despite its rarity, sarcoma ranked third overall among the number of patients' samples sent for sequencing. Herein, we recount the lessons learned...