Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma

• Main Authors: Karmele Valencia (Author), Cristina Sainz (Author), Cristina Bértolo (Author), Gabriel de Biurrun (Author), Jackeline Agorreta (Author), Arantza Azpilikueta (Author), Marta Larrayoz (Author), Graziella Bosco (Author), Carolina Zandueta (Author), Miriam Redrado (Author), Esther Redín (Author), Francisco Exposito (Author), Diego Serrano (Author), Mirari Echepare (Author), Daniel Ajona (Author), Ignacio Melero (Author), Ruben Pio (Author), Roman Thomas (Author), Alfonso Calvo (Author), Luis M. Montuenga (Author)
• Format: Book
• Published: The Company of Biologists, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is a paucity of adequate mouse models and cell lines available to study lung squamous cell carcinoma (LUSC). We have generated and characterized two models of phenotypically different transplantable LUSC cell lines, i.e. UN-SCC679 and UN-SCC680, derived from A/J mice that had been chemically i...