Brazilian Expert Consensus for NTRK Gene Fusion Testing in Solid Tumors

• Main Authors: Mariana Petaccia de Macedo (Author), Ellen Caroline Toledo Nascimento (Author), Fernando Augusto Soares (Author), Fernando Costa Santini (Author), Felipe D'Almeida Costa (Author), Isabela Werneck da Cunha (Author), Rodrigo Ramella Munhoz (Author), Pedro De Marchi (Author), Thiago William Carnier Jorge (Author), Kátia Ramos Moreira Leite (Author)
• Format: Book
• Published: SAGE Publishing, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oncogenic neurotrophic tropomyosin receptor kinase gene fusions occur in less than 1% of common cancers. These mutations have emerged as new biomarkers in cancer genomic profiling with the approval of selective drugs against tropomyosin receptor kinase fusion proteins. Nevertheless, the optimal path...