Dual gene‐activated dermal scaffolds regulate angiogenesis and wound healing by mediating the coexpression of VEGF and angiopoietin‐1

• Main Authors: Tingting Weng (Author), Min Yang (Author), Wei Zhang (Author), Ronghua Jin (Author), Sizhan Xia (Author), Manjia Zhang (Author), Pan Wu (Author), Xiaojie He (Author), Chunmao Han (Author), Xiong Zhao (Author), Xingang Wang (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The vascularization of dermal substitutes is a key challenge in efforts to heal deep skin defects. In this study, dual gene‐activated dermal scaffolds (DGADSs‐1) were fabricated by loading nanocomposite particles of polyethylenimine (PEI)/multiple plasmid DNAs (pDNAs) encoding vascular endo...