Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.

• Main Authors: Estefania Calvo-Álvarez (Author), Nestor Adrian Guerrero (Author), Raquel Alvarez-Velilla (Author), Christopher Fernández Prada (Author), Jose María Requena (Author), Carmen Punzón (Author), Miguel Ángel Llamas (Author), Francisco J Arévalo (Author), Luis Rivas (Author), Manuel Fresno (Author), Yolanda Pérez-Pertejo (Author), Rafael Balaña-Fouce (Author), Rosa M Reguera (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Leishmania major cutaneous leishmaniasis is an infectious zoonotic disease. It is produced by a digenetic parasite, which resides in the phagolysosomal compartment of different mammalian macrophage populations. There is an urgent need to develop new therapies (drugs) against this neglect...